The sciatic nerve is the longest nerve in the human body, extending from the lower back down through the legs and feet. When this nerve becomes irritated, inflamed, or injured, you may experience a variety of unpleasant symptoms such as pain, numbness, weakness, tingling, and/or a burning sensation that radiates from the lower back and can affect the hip, buttock, leg, and/or foot. The greatest risk factors for developing sciatica include age, excess weight, and lifestyle considerations, such as jobs that require heavy lifting, or alternately, extended periods of sitting. Sciatica can be temporary, or it may develop into a chronic condition without treatment.